Polycystic ovarian syndrome, consortium definition

PheWeb

E4_PCOS_CONCORTIUM

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

Apply sex-specific rule

Sex only females

219462

Check conditions None

219462

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L68.0#, N92.5, N92.6

Hospital discharge: ICD-9 626|7041

Hospital discharge: ICD-8 626|70405

Hospital discharge: excluded ICD-10 E2839|E24|E23[0-4]|E25|F50|F11|D25|D352|E22|E221|C56|D27|Q96|N643|C74

Hospital discharge: excluded ICD-9 2563|25631|2568|2550|2580|2434A|2532[AB]2552|3071A|3072A|3075[AB]|304|2180|253X|2531X|2531A|2395|220|7586|2531A|2270|1940

Hospital discharge: excluded ICD-8 2561|255|258|2561|255|3065|304|21899|2262|253|253|183|22099|7595|253|2260

Cause of death: ICD-10 L68.0#, N92.5, N92.6

Cause of death: ICD-9 626|7041

Cause of death: ICD-8 626|70405

Cause of death: excluded ICD-10 E2839|E24|E23[0-4]|E25|F50|F11|D25|D352|E22|E221|C56|D27|Q96|N643|C74

Cause of death: excluded ICD-9 2563|25631|2568|2550|2580|2434A|2532[AB]2552|3071A|3072A|3075[AB]|304|2180|253X|2531X|2531A|2395|220|7586|2531A|2270|1940

Cause of death: excluded ICD-8 2561|255|258|2561|255|3065|304|21899|2262|253|253|183|22099|7595|253|2260

2 out of 7 registries used, show all original rules.

23716

Check minimum number of events None

23716

Include endpoints

E4_PCOS

N14_MENSIRREG

32714

Remove individuals based on genotype QC

31548

E4_PCOS_CONCORTIUM

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF6v3

NAME	E4_PCOS_CONCORTIUM
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX	2
INCLUDE	E4_PCOS\|N14_MENSIRREG
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	N925\|N926\|L680
HD_ICD_9	626\|7041
HD_ICD_8	626\|70405
HD_ICD_10_EXCL	E2839\|E24\|E23[0-4]\|E25\|F50\|F11\|D25\|D352\|E22\|E221\|C56\|D27\|Q96\|N643\|C74
HD_ICD_9_EXCL	2563\|25631\|2568\|2550\|2580\|2434A\|2532[AB]2552\|3071A\|3072A\|3075[AB]\|304\|2180\|253X\|2531X\|2531A\|2395\|220\|7586\|2531A\|2270\|1940
HD_ICD_8_EXCL	2561\|255\|258\|2561\|255\|3065\|304\|21899\|2262\|253\|253\|183\|22099\|7595\|253\|2260
COD_MAINONLY
COD_ICD_10	N925\|N926\|L680
COD_ICD_9	626\|7041
COD_ICD_8	626\|70405
COD_ICD_10_EXCL	E2839\|E24\|E23[0-4]\|E25\|F50\|F11\|D25\|D352\|E22\|E221\|C56\|D27\|Q96\|N643\|C74
COD_ICD_9_EXCL	2563\|25631\|2568\|2550\|2580\|2434A\|2532[AB]2552\|3071A\|3072A\|3075[AB]\|304\|2180\|253X\|2531X\|2531A\|2395\|220\|7586\|2531A\|2270\|1940
COD_ICD_8_EXCL	2561\|255\|258\|2561\|255\|3065\|304\|21899\|2262\|253\|253\|183\|22099\|7595\|253\|2260
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Polycystic ovarian syndrome, consortium definition based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	31548	31548	-
Unadjusted prevalence (%)	8.37	14.97	-
Mean age at first event (years)	38.37	38.37	-

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.54 [0.47, 0.62]	2.6e-18	1774
15 years	0.00	0.39 [0.34, 0.45]	5.3e-42	631
5 years	0.00	0.29 [0.23, 0.36]	1.2e-27	98
1 year	0.00	0.33 [0.21, 0.53]	3.2e-6	19

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_PCOS_CONCORTIUM – Polycystic ovarian syndrome, consortium definition
GWS hits: 6

Survival analyses between endpoints

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Plot

before Polycystic ovarian syndrome, consortium definition
after Polycystic ovarian syndrome, consortium definition

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Table

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Drugs most likely to be purchased after Polycystic ovarian syndrome, consortium definition

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Endpoint not on priority list, no data to show.

≡ Risteys

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