Polycystic ovarian syndrome, consortium definition

E4_PCOS_CONCORTIUM

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule

Sex only females

219462

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Check conditions None

219462

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L68.0#, N92.5, N92.6
Hospital discharge: ICD-9 626|7041
Hospital discharge: ICD-8 626|70405
Hospital discharge: excluded ICD-10 E2839|E24|E23[0-4]|E25|F50|F11|D25|D352|E22|E221|C56|D27|Q96|N643|C74
Hospital discharge: excluded ICD-9 2563|25631|2568|2550|2580|2434A|2532[AB]2552|3071A|3072A|3075[AB]|304|2180|253X|2531X|2531A|2395|220|7586|2531A|2270|1940
Hospital discharge: excluded ICD-8 2561|255|258|2561|255|3065|304|21899|2262|253|253|183|22099|7595|253|2260
Cause of death: ICD-10 L68.0#, N92.5, N92.6
Cause of death: ICD-9 626|7041
Cause of death: ICD-8 626|70405
Cause of death: excluded ICD-10 E2839|E24|E23[0-4]|E25|F50|F11|D25|D352|E22|E221|C56|D27|Q96|N643|C74
Cause of death: excluded ICD-9 2563|25631|2568|2550|2580|2434A|2532[AB]2552|3071A|3072A|3075[AB]|304|2180|253X|2531X|2531A|2395|220|7586|2531A|2270|1940
Cause of death: excluded ICD-8 2561|255|258|2561|255|3065|304|21899|2262|253|253|183|22099|7595|253|2260

2 out of 7 registries used, show all original rules.

23716

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Check minimum number of events None

23716

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Include endpoints

32714

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Remove individuals based on genotype QC

31548

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E4_PCOS_CONCORTIUM

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF6v3

Summary Statistics

Key figures

All Female Male
Number of individuals 31548 31548 -
Unadjusted prevalence (%) 8.37 14.97 -
Mean age at first event (years) 38.37 38.37 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.54 [0.47, 0.62] 2.6e-18 1774
15 years 0.00 0.39 [0.34, 0.45] 5.3e-42 631
5 years 0.00 0.29 [0.23, 0.36] 1.2e-27 98
1 year 0.00 0.33 [0.21, 0.53] 3.2e-6 19

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_PCOS_CONCORTIUM – Polycystic ovarian syndrome, consortium definition
GWS hits: 6

Survival analyses between endpoints

Plot

before Polycystic ovarian syndrome, consortium definition
after Polycystic ovarian syndrome, consortium definition

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Drugs most likely to be purchased after Polycystic ovarian syndrome, consortium definition

Endpoint not on priority list, no data to show.