Nutritional marasmus


marasmus: The lack of sufficient energy or protein to meet the body's metabolic demands, as a result of either an inadequate dietary intake of protein, intake of poor quality dietary protein, increased demands due to disease, or increased nutrient losses.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E41
Hospital discharge: ICD-9 261
Cause of death: ICD-10 E41
Cause of death: ICD-9 261

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude E4_MALNUTRITION

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E40-E46
Name in latin Malnutritio gravis ex deficientia energetica (marasmus nutritionalis)

Summary Statistics

Key figures

All Female Male
Number of individuals 31 17 14
Unadjusted prevalence (%) 0.01 0.01 0.01
Mean age at first event (years) 48.58 45.55 52.25


Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: E4_MARASMUS – Nutritional marasmus
GWS hits:

Survival analyses between endpoints


before Nutritional marasmus
after Nutritional marasmus

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Drugs most likely to be purchased after Nutritional marasmus

Endpoint not on priority list, no data to show.