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Type 1 diabetes with other specified/multiple/unspecified complications

MESH PheWeb

E4_DM1NASCOMP

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E10.6, E10.6+M14.2, E10.6+M14.6, E10.7, E10.8
Hospital discharge: ICD-9 2507B|2508B
Cause of death: ICD-10 E10.6, E10.6+M14.2, E10.6+M14.6, E10.7, E10.8
Cause of death: ICD-9 2507B|2508B
KELA reimbursements: KELA codes ANY
KELA reimbursements: ICD-10 E10

3 out of 7 registries used, show all original rules.

6423

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Check minimum number of events None

6423

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Include endpoints None

6423

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Remove individuals based on genotype QC

6234

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E4_DM1NASCOMP

Control definitions

Control exclude E4_DIABETES

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 6234 2973 3261
Unadjusted prevalence (%) 1.65 1.41 1.96
Mean age at first event (years) 37.28 35.05 39.31

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 6.38 [4.84, 8.41] 1.4e-39 721
15 years 0.02 3.84 [2.92, 5.06] 1.1e-21 340
5 years 0.01 5.51 [4.30, 7.06] 2.4e-41 164
1 year 0.00 11.77 [8.60, 16.11] 1.6e-53 70

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_DM1NASCOMP – Type 1 diabetes with other specified/multiple/unspecified complications
GWS hits: 32

Survival analyses between endpoints

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Plot

before Type 1 diabetes with other specified/multiple/unspecified complications
after Type 1 diabetes with other specified/multiple/unspecified complications

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Type 1 diabetes with other specified/multiple/unspecified complications

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Endpoint not on priority list, no data to show.