Diabetic hypoglycemia


diabetic retinopathy: A chronic, pathological complication associated with diabetes mellitus, where retinal damages are incurred due to microaneurysms in the vasculature of the retina, progressively leading to abnormal blood vessel growth, and swelling and leaking of fluid from blood vessels, resulting in vision loss or blindness.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E10.00, E11.00, E16.0#, E16.2
Hospital discharge: ICD-9 2510B|2512
Cause of death: ICD-10 E10.00, E11.00, E16.0#, E16.2
Cause of death: ICD-9 2510B|2512

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude DM_COMORB

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 7332 3022 4310
Unadjusted prevalence (%) 1.94 1.43 2.59
Mean age at first event (years) 54.71 51.51 56.96


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.29 [4.09, 6.86] 1.7e-36 2252
15 years 0.02 2.44 [1.88, 3.17] 1.9e-11 872
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: DM_HYPOGLYC – Diabetic hypoglycemia
GWS hits: 6

Survival analyses between endpoints


before Diabetic hypoglycemia
after Diabetic hypoglycemia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diabetic hypoglycemia

Endpoint not on priority list, no data to show.