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Hereditary factor VIII deficiency

DOID EFO MESH PheWeb

D3_HEREDFVIIIDEF

obsolete_factor VIII deficiency: An X-linked disease that has_material_basis_in Factor VIII deficiency, which results in the formation of fibrin deficient clots which makes coagulation much more prolonged. The disease is inherited as an X-linked recessive trait.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D66
Hospital discharge: ICD-9 2860
Hospital discharge: ICD-8 2860
Cause of death: ICD-10 D66
Cause of death: ICD-9 2860
Cause of death: ICD-8 2860

2 out of 7 registries used, show all original rules.

79

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Check minimum number of events None

79

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Include endpoints None

79

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Remove individuals based on genotype QC

77

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D3_HEREDFVIIIDEF

Control definitions

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D65-D69
Name in latin Deficientia hereditaria factoris VIII

Similar endpoints

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List of similar endpoints to Hereditary factor VIII deficiency based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 77 32 45
Unadjusted prevalence (%) 0.02 0.02 0.03
Mean age at first event (years) 29.70 36.77 24.67

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_HEREDFVIIIDEF – Hereditary factor VIII deficiency
GWS hits:

Survival analyses between endpoints

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Not a core endpoint, no data to show.

Drugs most likely to be purchased after Hereditary factor VIII deficiency

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Endpoint not on priority list, no data to show.