Iron deficiency anaemia secondary to blood loss (chronic)

DOID EFO MESH SNOMED PheWeb

D3_ANAEMIA_IRONDEF_BLOODLOSS

hemolytic anemia: Hemolytic anemia that is not mediated by immune mechanisms.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D50.0

Hospital discharge: ICD-9 2800

Hospital discharge: ICD-8 2800

Cause of death: ICD-10 D50.0

Cause of death: ICD-9 2800

Cause of death: ICD-8 2800

2 out of 7 registries used, show all original rules.

5016

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Check minimum number of events None

5016

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Include endpoints None

5016

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Remove individuals based on genotype QC

4852

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D3_ANAEMIA_IRONDEF_BLOODLOSS

Control definitions

Control exclude D3_NUTRIANAEMIA

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D50

Name in latin Anaemia posthaemorrhagica

NAME	D3_ANAEMIA_IRONDEF_BLOODLOSS
CONTROL_EXCLUDE	D3_NUTRIANAEMIA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D500
HD_ICD_9	2800
HD_ICD_8	2800
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D500
COD_ICD_9	2800
COD_ICD_8	2800
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Iron deficiency anaemia secondary to blood loss (chronic) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	4852	2814	2038
Unadjusted prevalence (%)	1.29	1.33	1.23
Mean age at first event (years)	55.48	48.88	64.59

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	3.99 [2.89, 5.51]	4.3e-17	1117
15 years	0.01	1.53 [1.20, 1.95]	5.2e-4	299
5 years	0.01	4.87 [4.07, 5.82]	1.5e-67	400
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_ANAEMIA_IRONDEF_BLOODLOSS – Iron deficiency anaemia secondary to blood loss (chronic)
GWS hits: 2

Survival analyses between endpoints

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Plot

before Iron deficiency anaemia secondary to blood loss (chronic)
after Iron deficiency anaemia secondary to blood loss (chronic)

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Table

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Drugs most likely to be purchased after Iron deficiency anaemia secondary to blood loss (chronic)

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Endpoint not on priority list, no data to show.