Acute posthaemorrhagic anaemia

D3_ACUTEPOSTBLEEDANAEMIA

Anemia, Hemolytic, Autoimmune: Autoimmune hemolytic anemia (AIHA) is an autoimmune disorder in which various types of auto-antibodies are directed against red blood cells causing their survival to be shortened and resulting in hemolytic anemia.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D62
Hospital discharge: ICD-9 2851A
Cause of death: ICD-10 D62
Cause of death: ICD-9 2851A

2 out of 7 registries used, show all original rules.

1015

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Check minimum number of events None

1015

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Include endpoints None

1015

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Remove individuals based on genotype QC

976

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D3_ACUTEPOSTBLEEDANAEMIA

Control definitions

Control exclude D3_APLASTICANDOTHANAEMIA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D60-D64
Name in latin Anaemia posthaemorrhagica acuta

Summary Statistics

Key figures

All Female Male
Number of individuals 976 445 531
Unadjusted prevalence (%) 0.26 0.21 0.32
Mean age at first event (years) 65.22 60.94 68.81

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 6.13 [3.95, 9.51] 6.3e-16 384
15 years 0.01 1.96 [1.39, 2.76] 1.1e-4 95
5 years 0.01 5.33 [3.77, 7.54] 2.7e-21 126
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: D3_ACUTEPOSTBLEEDANAEMIA – Acute posthaemorrhagic anaemia
GWS hits:

Survival analyses between endpoints

Plot

before Acute posthaemorrhagic anaemia
after Acute posthaemorrhagic anaemia

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Drugs most likely to be purchased after Acute posthaemorrhagic anaemia

Endpoint not on priority list, no data to show.