Other leukaemias of specified cell type

CD2_OTHER_LEUKAEMIA_SPECIFIED

leukemia: A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 C94
Hospital discharge: ICD-9 207[0-8]
Hospital discharge: ICD-8 207[0-2]
Cause of death: ICD-10 C94
Cause of death: ICD-9 207[0-8]
Cause of death: ICD-8 207[0-2]

2 out of 7 registries used, show all original rules.

66

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Check minimum number of events None

66

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Include endpoints None

66

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Remove individuals based on genotype QC

64

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CD2_OTHER_LEUKAEMIA_SPECIFIED

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF8
Parent code in ICD-10 C81-C96
Name in latin Aliae leuc(h)aemiae typo cellulari specificato

Similar endpoints

List of similar endpoints to Other leukaemias of specified cell type based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 64 35 29
Unadjusted prevalence (%) 0.02 0.02 0.02
Mean age at first event (years) 48.33 45.90 51.26

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CD2_OTHER_LEUKAEMIA_SPECIFIED – Other leukaemias of specified cell type
GWS hits:

Survival analyses between endpoints

Plot

before Other leukaemias of specified cell type
after Other leukaemias of specified cell type

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Drugs most likely to be purchased after Other leukaemias of specified cell type

Endpoint not on priority list, no data to show.