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Multiple myeloma and malignant plasma cell neoplasms

CD2_MULTIPLE_MYELOMA_PLASMA_CELL

multiple myeloma: A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 C90
Hospital discharge: ICD-9 203
Hospital discharge: ICD-8 203
Cause of death: ICD-10 C90
Cause of death: ICD-9 203
Cause of death: ICD-8 203

2 out of 7 registries used, show all original rules.

1292

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Check minimum number of events None

1292

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Include endpoints None

1292

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Remove individuals based on genotype QC

1249

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CD2_MULTIPLE_MYELOMA_PLASMA_CELL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF8
Parent code in ICD-10 C81-C96
Name in latin Myeloma multiplex et neoplasmata maligna plasmacytorum

Similar endpoints

List of similar endpoints to Multiple myeloma and malignant plasma cell neoplasms based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 1249 548 701
Unadjusted prevalence (%) 0.33 0.26 0.42
Mean age at first event (years) 66.81 65.43 67.90

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: CD2_MULTIPLE_MYELOMA_PLASMA_CELL – Multiple myeloma and malignant plasma cell neoplasms
GWS hits:

Survival analyses between endpoints

Plot

before Multiple myeloma and malignant plasma cell neoplasms
after Multiple myeloma and malignant plasma cell neoplasms

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Drugs most likely to be purchased after Multiple myeloma and malignant plasma cell neoplasms