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Leukaemia of unspecified cell type

DOID EFO MESH SNOMED PheWeb

CD2_LEUKAEMIA_NAS

leukemia: A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 C95
Hospital discharge: ICD-9 20[7-8]
Hospital discharge: ICD-8 207
Hospital discharge: excluded ICD-9 207[0-8]
Hospital discharge: excluded ICD-8 207[0-2]
Cause of death: ICD-10 C95
Cause of death: ICD-9 20[7-8]
Cause of death: ICD-8 207
Cause of death: excluded ICD-9 207[0-8]
Cause of death: excluded ICD-8 207[0-2]

2 out of 7 registries used, show all original rules.

244

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Check minimum number of events None

244

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Include endpoints None

244

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Remove individuals based on genotype QC

220

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CD2_LEUKAEMIA_NAS

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF8
Parent code in ICD-10 C81-C96
Name in latin Leuc(h)aemiae typo cellulari non specificato

Similar endpoints

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List of similar endpoints to Leukaemia of unspecified cell type based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 220 95 125
Unadjusted prevalence (%) 0.06 0.05 0.08
Mean age at first event (years) 56.26 52.43 59.17

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_LEUKAEMIA_NAS – Leukaemia of unspecified cell type
GWS hits:

Survival analyses between endpoints

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Plot

before Leukaemia of unspecified cell type
after Leukaemia of unspecified cell type

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Drugs most likely to be purchased after Leukaemia of unspecified cell type

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Endpoint not on priority list, no data to show.