Hodgkin lymphoma


non-Hodgkins lymphoma: Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 C81
Hospital discharge: ICD-9 201
Cause of death: ICD-10 C81
Cause of death: ICD-9 201

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 C81-C96
Name in latin Morbus Hodgkin

Summary Statistics

Key figures

All Female Male
Number of individuals 780 366 414
Unadjusted prevalence (%) 0.21 0.17 0.25
Mean age at first event (years) 46.92 42.08 51.21


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.74 [1.92, 7.31] 1.1e-4 121
15 years 0.02 2.39 [1.40, 4.07] 1.3e-3 46
5 years 0.01 6.04 [3.68, 9.92] 1.2e-12 34
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: CD2_HODGKIN_LYMPHOMA – Hodgkin lymphoma
GWS hits: 1

Survival analyses between endpoints


before Hodgkin lymphoma
after Hodgkin lymphoma

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Drugs most likely to be purchased after Hodgkin lymphoma

Endpoint not on priority list, no data to show.