≡ Risteys
R9

Documentation Changelog GitHub Contact & Feedback

Hodgkin lymphoma

DOID EFO MESH PheWeb

CD2_HODGKIN_LYMPHOMA

non-Hodgkins lymphoma: Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage.

Endpoint definition

↥
FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 C81
Hospital discharge: ICD-9 201
Cause of death: ICD-10 C81
Cause of death: ICD-9 201

2 out of 7 registries used, show all original rules.

810

diagram downward connector

Check minimum number of events None

810

diagram downward connector

Include endpoints None

810

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

780

diagram downward connector
CD2_HODGKIN_LYMPHOMA

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 C81-C96
Name in latin Morbus Hodgkin

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 780 366 414
Unadjusted prevalence (%) 0.21 0.17 0.25
Mean age at first event (years) 46.92 42.08 51.21

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.74 [1.92, 7.31] 1.1e-4 121
15 years 0.02 2.39 [1.40, 4.07] 1.3e-3 46
5 years 0.01 6.04 [3.68, 9.92] 1.2e-12 34
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: CD2_HODGKIN_LYMPHOMA – Hodgkin lymphoma
GWS hits: 1

Survival analyses between endpoints

↥

Plot

before Hodgkin lymphoma
after Hodgkin lymphoma

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hodgkin lymphoma

↥

Endpoint not on priority list, no data to show.