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Benign neoplasm: Sigmoid colon

DOID EFO MESH SNOMED PheWeb

CD2_BENIGN_SIGMOID_COLON

sigmoid neoplasm: Tumors or cancer of the sigmoid colon.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D12.5&
Hospital discharge: ICD-8 21136
Cause of death: ICD-10 D12.5&
Cause of death: ICD-8 21136

2 out of 7 registries used, show all original rules.

5038

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Check minimum number of events None

5038

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Include endpoints None

5038

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Remove individuals based on genotype QC

4876

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CD2_BENIGN_SIGMOID_COLON

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D12
Name in latin Neoplasma benignum coli sigmoidei

Similar endpoints

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List of similar endpoints to Benign neoplasm: Sigmoid colon based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 4876 2313 2563
Unadjusted prevalence (%) 1.29 1.10 1.54
Mean age at first event (years) 64.41 63.09 65.59

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.18 [1.53, 3.13] 2.0e-5 617
15 years 0.01 1.25 [0.94, 1.67] 1.3e-1 276
5 years 0.00 2.84 [2.26, 3.57] 3.3e-19 221
1 year 0.00 4.65 [3.45, 6.26] 5.4e-24 72

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_BENIGN_SIGMOID_COLON – Benign neoplasm: Sigmoid colon
GWS hits: 3

Survival analyses between endpoints

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Plot

before Benign neoplasm: Sigmoid colon
after Benign neoplasm: Sigmoid colon

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Drugs most likely to be purchased after Benign neoplasm: Sigmoid colon

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Endpoint not on priority list, no data to show.