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Benign neoplasm: Rectosigmoid junction

DOID EFO MESH SNOMED PheWeb

CD2_BENIGN_RECTOSIGMOID_JUNC

sigmoid neoplasm: Tumors or cancer of the sigmoid colon.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D12.7&
Cause of death: ICD-10 D12.7&

2 out of 7 registries used, show all original rules.

1014

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Check minimum number of events None

1014

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Include endpoints None

1014

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Remove individuals based on genotype QC

982

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CD2_BENIGN_RECTOSIGMOID_JUNC

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D12
Name in latin Neoplasma benignum junctionis rectosigmoideae

Similar endpoints

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List of similar endpoints to Benign neoplasm: Rectosigmoid junction based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 982 465 517
Unadjusted prevalence (%) 0.26 0.22 0.31
Mean age at first event (years) 65.17 64.50 65.78

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.82 [1.82, 4.38] 3.9e-6 124
15 years 0.01 1.46 [0.91, 2.34] 1.2e-1 60
5 years 0.00 2.30 [1.29, 4.08] 4.5e-3 43
1 year 0.00 3.23 [1.55, 6.75] 1.8e-3 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_BENIGN_RECTOSIGMOID_JUNC – Benign neoplasm: Rectosigmoid junction
GWS hits: 2

Survival analyses between endpoints

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Plot

before Benign neoplasm: Rectosigmoid junction
after Benign neoplasm: Rectosigmoid junction

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Drugs most likely to be purchased after Benign neoplasm: Rectosigmoid junction

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Endpoint not on priority list, no data to show.