Benign neoplasm: Endocrine pancreas

CD2_BENIGN_ENDOCRINE_PANCREAS

pancreatic neuroendocrine tumor: Pancreatic endocrine tumor, also known as pancreatic neuroendocrine tumor (PNET), describes a group of endocrine tumors originating in the pancreas that are usually indolent and benign, but may have the potential to be malignant. They can be functional, exhibiting a hormonal hypersecretion syndrome, but can be non-functional presenting with non-specific symptoms and include insulinoma, glucagonoma, VIPoma, somatostatinoma (SSoma), PPoma and Zollinger-Ellison syndrome (ZES, or gastrinoma) and other ectopic hormone producing tumors (such as GRFoma) (see these terms).

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D13.7&
Hospital discharge: ICD-9 2117
Cause of death: ICD-10 D13.7&
Cause of death: ICD-9 2117

2 out of 7 registries used, show all original rules.

139

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Check minimum number of events None

139

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Include endpoints None

139

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Remove individuals based on genotype QC

135

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CD2_BENIGN_ENDOCRINE_PANCREAS

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D13
Name in latin Neoplasma benignum partis endocrinae pancreatis

Similar endpoints

List of similar endpoints to Benign neoplasm: Endocrine pancreas based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 135 57 78
Unadjusted prevalence (%) 0.04 0.03 0.05
Mean age at first event (years) 62.78 59.31 65.31

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CD2_BENIGN_ENDOCRINE_PANCREAS – Benign neoplasm: Endocrine pancreas
GWS hits:

Survival analyses between endpoints

Plot

before Benign neoplasm: Endocrine pancreas
after Benign neoplasm: Endocrine pancreas

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Drugs most likely to be purchased after Benign neoplasm: Endocrine pancreas

Endpoint not on priority list, no data to show.