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Benign neoplasm: Descending colon

DOID EFO MESH PheWeb

CD2_BENIGN_DESCENDING_COLON

colonic neoplasm: A benign or malignant neoplasm that affects the colon. Representative examples of benign neoplasms include lipoma and leiomyoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma. Colonic adenomas always exhibit epithelial dysplasia and are considered premalignant neoplasms.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D12.4&
Hospital discharge: ICD-8 21135
Cause of death: ICD-10 D12.4&
Cause of death: ICD-8 21135

2 out of 7 registries used, show all original rules.

1630

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Check minimum number of events None

1630

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Include endpoints None

1630

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Remove individuals based on genotype QC

1571

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CD2_BENIGN_DESCENDING_COLON

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D12
Name in latin Neoplasma benignum coli descendentis

Similar endpoints

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List of similar endpoints to Benign neoplasm: Descending colon based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 1571 703 868
Unadjusted prevalence (%) 0.42 0.33 0.52
Mean age at first event (years) 65.73 63.53 67.52

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.11 [1.16, 3.83] 1.5e-2 183
15 years 0.01 1.13 [0.63, 2.00] 6.9e-1 85
5 years 0.00 2.52 [1.60, 3.98] 7.1e-5 73
1 year 0.00 2.97 [1.61, 5.49] 5.2e-4 16

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_BENIGN_DESCENDING_COLON – Benign neoplasm: Descending colon
GWS hits:

Survival analyses between endpoints

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Plot

before Benign neoplasm: Descending colon
after Benign neoplasm: Descending colon

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Drugs most likely to be purchased after Benign neoplasm: Descending colon

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Endpoint not on priority list, no data to show.