Benign neoplasm: Choroid

CD2_BENIGN_CHOROID

choroid cancer: Tumors of the choroid; most common intraocular tumors are malignant melanomas of the choroid. These usually occur after puberty and increase in incidence with advancing age. Most malignant melanomas of the uveal tract develop from benign melanomas (nevi).

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D31.3&
Hospital discharge: ICD-9 2246
Cause of death: ICD-10 D31.3&
Cause of death: ICD-9 2246

2 out of 7 registries used, show all original rules.

1374

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Check minimum number of events None

1374

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Include endpoints None

1374

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Remove individuals based on genotype QC

1324

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CD2_BENIGN_CHOROID

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D31
Name in latin Neoplasma benignum chorioideae

Summary Statistics

Key figures

All Female Male
Number of individuals 1324 785 539
Unadjusted prevalence (%) 0.35 0.37 0.32
Mean age at first event (years) 62.98 60.97 65.92

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.62 [0.79, 3.33] 1.9e-1 81
15 years 0.01 0.99 [0.49, 1.99] 9.7e-1 40
5 years 0.00 1.40 [0.64, 3.09] 4.0e-1 27
1 year 0.00 2.41 [1.02, 5.72] 4.6e-2 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CD2_BENIGN_CHOROID – Benign neoplasm: Choroid
GWS hits: 1

Survival analyses between endpoints

Plot

before Benign neoplasm: Choroid
after Benign neoplasm: Choroid

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Drugs most likely to be purchased after Benign neoplasm: Choroid

Endpoint not on priority list, no data to show.