Benign neoplasm: Bronchus and lung

DOID EFO MESH PheWeb

CD2_BENIGN_BRONCHUS_LUNG

oropharynx cancer: A primary or metastatic malignant neoplasm that affects the oropharynx.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D14.3&

Hospital discharge: ICD-9 2123

Hospital discharge: ICD-8 2123

Cause of death: ICD-10 D14.3&

Cause of death: ICD-9 2123

Cause of death: ICD-8 2123

2 out of 7 registries used, show all original rules.

342

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Check minimum number of events None

342

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Include endpoints None

342

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Remove individuals based on genotype QC

331

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CD2_BENIGN_BRONCHUS_LUNG

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D14

Name in latin Neoplasma benignum bronchi

NAME	CD2_BENIGN_BRONCHUS_LUNG
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D143
HD_ICD_9	2123
HD_ICD_8	2123
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D143
COD_ICD_9	2123
COD_ICD_8	2123
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Benign neoplasm: Bronchus and lung based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Benign neoplasm: Bronchus and lung (controls excluding all cancers)

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	331	135	196
Unadjusted prevalence (%)	0.09	0.06	0.12
Mean age at first event (years)	55.87	52.20	58.40

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.44 [0.13, 1.47]	1.8e-1	58
15 years	0.00	0.37 [0.12, 1.13]	8.2e-2	23
5 years	0.00	1.08 [0.40, 2.91]	8.7e-1	15
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_BENIGN_BRONCHUS_LUNG – Benign neoplasm: Bronchus and lung
GWS hits:

Survival analyses between endpoints

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Plot

before Benign neoplasm: Bronchus and lung
after Benign neoplasm: Bronchus and lung

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Table

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Drugs most likely to be purchased after Benign neoplasm: Bronchus and lung

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Endpoint not on priority list, no data to show.