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Benign neoplasm: Adrenal gland

DOID EFO MESH PheWeb

CD2_BENIGN_ADRENAL

extra-adrenal sympathetic paraganglioma: A benign or malignant sympathetic paraganglioma arising from paraganglia outside the adrenal gland. Clinical symptoms are related to secretion of catecholamines. Representative examples include the superior and inferior paraaortic and bladder paragangliomas.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D35.0&
Hospital discharge: ICD-9 2270
Hospital discharge: ICD-8 2260
Cause of death: ICD-10 D35.0&
Cause of death: ICD-9 2270
Cause of death: ICD-8 2260

2 out of 7 registries used, show all original rules.

1850

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Check minimum number of events None

1850

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Include endpoints None

1850

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Remove individuals based on genotype QC

1790

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CD2_BENIGN_ADRENAL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D35
Name in latin Neoplasma benignum glandulae suprarenalis

Similar endpoints

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List of similar endpoints to Benign neoplasm: Adrenal gland based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 1790 1035 755
Unadjusted prevalence (%) 0.47 0.49 0.45
Mean age at first event (years) 62.39 60.51 64.96

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.19 [2.50, 7.02] 5.4e-8 126
15 years 0.01 2.20 [1.35, 3.60] 1.6e-3 52
5 years 0.01 4.74 [2.77, 8.09] 1.2e-8 55
1 year 0.00 5.94 [2.99, 11.83] 3.8e-7 14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_BENIGN_ADRENAL – Benign neoplasm: Adrenal gland
GWS hits: 2

Survival analyses between endpoints

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Plot

before Benign neoplasm: Adrenal gland
after Benign neoplasm: Adrenal gland

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Drugs most likely to be purchased after Benign neoplasm: Adrenal gland

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Endpoint not on priority list, no data to show.