Malignant neoplasm of thyroid gland (controls excluding all cancers)

C3_THYROID_GLAND_EXALLC

No definition available.

Endpoint definition

FinnGen phenotype data

individuals

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Apply sex-specific rule None

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Check conditions None

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Check pre-conditions, main-only, mode, registry filters

Cause of death: ICD-10 C73
Cause of death: ICD-9 193
Cause of death: ICD-8 193
Cancer registry: Topography ICD-O-3 C73
Cancer registry: Morphology ICD-O-3 ANY
Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints None

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Remove individuals based on genotype QC

1783

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C3_THYROID_GLAND_EXALLC

Control definitions

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9

Similar endpoints

List of similar endpoints to Malignant neoplasm of thyroid gland (controls excluding all cancers) based on the number of shared cases.

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Summary Statistics

Key figures

All Female Male
Number of individuals 1783 1327 456
Unadjusted prevalence (%) 0.47 0.63 0.27
Mean age at first event (years) 50.32 48.58 55.36

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.93 [1.16, 3.21] 1.1e-2 146
15 years 0.01 0.99 [0.57, 1.72] 9.8e-1 45
5 years 0.00 3.15 [1.95, 5.09] 2.8e-6 41
1 year 0.00 13.04 [7.62, 22.31] 7.3e-21 33

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_THYROID_GLAND_EXALLC – Malignant neoplasm of thyroid gland (controls excluding all cancers)
GWS hits: 8

Survival analyses between endpoints

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before Malignant neoplasm of thyroid gland (controls excluding all cancers)
after Malignant neoplasm of thyroid gland (controls excluding all cancers)

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Drugs most likely to be purchased after Malignant neoplasm of thyroid gland (controls excluding all cancers)

Endpoint not on priority list, no data to show.