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Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum (controls excluding all cancers)

PheWeb

C3_RECTUM_ADENO_MUCINO_EXALLC

No definition available.

Endpoint definition

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FinnGen phenotype data

individuals

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Apply sex-specific rule None

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Check conditions None

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Check pre-conditions, main-only, mode, registry filters

Cause of death: ICD-10 C20.92&
Cancer registry: Topography ICD-O-3 C19|C20
Cancer registry: Morphology ICD-O-3 8140|8480
Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints None

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Remove individuals based on genotype QC

2437

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C3_RECTUM_ADENO_MUCINO_EXALLC

Control definitions

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze DF9
Name in latin Carcinoma in situ cavitatis oris, oesophagi sive ventriculi

Similar endpoints

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List of similar endpoints to Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 2437 870 1567
Unadjusted prevalence (%) 0.65 0.41 0.94
Mean age at first event (years) 66.83 65.08 67.80

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.27 [2.94, 6.21] 2.6e-14 685
15 years 0.01 1.69 [1.30, 2.21] 1.1e-4 198
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_RECTUM_ADENO_MUCINO_EXALLC – Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum (controls excluding all cancers)
GWS hits: 6

Survival analyses between endpoints

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Plot

before Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum (controls excluding all cancers)
after Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum (controls excluding all cancers)

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Drugs most likely to be purchased after Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum (controls excluding all cancers)

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Endpoint not on priority list, no data to show.