Malignant melanoma of skin (controls excluding all cancers)

C3_MELANOMA_SKIN_EXALLC

No definition available.

Endpoint definition

FinnGen phenotype data

individuals

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Apply sex-specific rule None

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Check conditions None

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Check pre-conditions, main-only, mode, registry filters

Cause of death: ICD-10 C43
Cause of death: ICD-9 172
Cause of death: ICD-8 172
Cancer registry: Topography ICD-O-3 C44
Cancer registry: Morphology ICD-O-3 8720|8721|8726|8730|8742|8743|8744|8745
Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints None

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Remove individuals based on genotype QC

2993

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C3_MELANOMA_SKIN_EXALLC

Control definitions

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9

Summary Statistics

Key figures

All Female Male
Number of individuals 2993 1452 1541
Unadjusted prevalence (%) 0.79 0.69 0.93
Mean age at first event (years) 59.91 56.20 63.41

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.96 [1.13, 3.39] 1.7e-2 442
15 years 0.01 0.87 [0.58, 1.32] 5.2e-1 124
5 years 0.00 3.55 [2.63, 4.79] 1.4e-16 165
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_MELANOMA_SKIN_EXALLC – Malignant melanoma of skin (controls excluding all cancers)
GWS hits: 9

Survival analyses between endpoints

Plot

before Malignant melanoma of skin (controls excluding all cancers)
after Malignant melanoma of skin (controls excluding all cancers)

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Drugs most likely to be purchased after Malignant melanoma of skin (controls excluding all cancers)

Endpoint not on priority list, no data to show.