Non-small cell lung cancer (controls excluding all cancers)

C3_LUNG_NONSMALL_EXALLC

No definition available.

Endpoint definition

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FinnGen phenotype data

individuals

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Apply sex-specific rule None

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Check conditions None

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 C34.[123457]

Cause of death: ICD-10 C34.[123457]

Cancer registry: Topography ICD-O-3 C34

Cancer registry: Morphology ICD-O-3 8046|8070|8140

Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints None

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Remove individuals based on genotype QC

4901

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C3_LUNG_NONSMALL_EXALLC

Control definitions

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF9

NAME	C3_LUNG_NONSMALL_EXALLC
CONTROL_EXCLUDE	C3_CANCER\|C3_CANCER_WIDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	C34.[123457]
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	C34.[123457]
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO	C34
CANC_TOPO_EXCL
CANC_MORPH	8046\|8070\|8140
CANC_MORPH_EXCL
CANC_BEHAV	3

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Or the full data table

Similar endpoints

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List of similar endpoints to Non-small cell lung cancer (controls excluding all cancers) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	4901	1364	3537
Unadjusted prevalence (%)	1.30	0.65	2.13
Mean age at first event (years)	70.26	67.43	71.36

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.28	21.21 [16.54, 27.18]	<1e-100	2548
15 years	0.01	1.92 [1.54, 2.40]	8.9e-9	169
5 years	0.02	14.64 [12.28, 17.45]	<1e-100	770
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_LUNG_NONSMALL_EXALLC – Non-small cell lung cancer (controls excluding all cancers)
GWS hits: 5

Survival analyses between endpoints

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Plot

before Non-small cell lung cancer (controls excluding all cancers)
after Non-small cell lung cancer (controls excluding all cancers)

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Table

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Drugs most likely to be purchased after Non-small cell lung cancer (controls excluding all cancers)

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Endpoint not on priority list, no data to show.