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Malignant neoplasm of heart, mediastinum and pleura

C3_HEART_MEDIASTINUM_PLEURA

Heart neoplasm: Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Cause of death: ICD-10 C38
Cause of death: ICD-9 16[3-4]
Cause of death: ICD-8 163[0-1]
Cause of death: excluded ICD-9 1640
Cancer registry: Topography ICD-O-3 C38
Cancer registry: Morphology ICD-O-3 ANY
Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

289

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Check minimum number of events None

289

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Include endpoints None

289

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Remove individuals based on genotype QC

283

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C3_HEART_MEDIASTINUM_PLEURA

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9

Similar endpoints

List of similar endpoints to Malignant neoplasm of heart, mediastinum and pleura based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 283 67 216
Unadjusted prevalence (%) 0.08 0.03 0.13
Mean age at first event (years) 66.34 57.02 69.23

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: C3_HEART_MEDIASTINUM_PLEURA – Malignant neoplasm of heart, mediastinum and pleura
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Malignant neoplasm of heart, mediastinum and pleura

Endpoint not on priority list, no data to show.