Diffuse large B-cell lymphoma (controls excluding all cancers)

C3_DLBCL_EXALLC

No definition available.

Endpoint definition

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FinnGen phenotype data

individuals

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Apply sex-specific rule None

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Check conditions

HLP_C3_DLBCL

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Check pre-conditions, main-only, mode, registry filters

Cause of death: ICD-10 C83.3

Cause of death: ICD-9 2000B

Cancer registry: Topography ICD-O-3 ANY

Cancer registry: Morphology ICD-O-3 9680

Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints

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Remove individuals based on genotype QC

1010

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C3_DLBCL_EXALLC

Control definitions

Control exclude C3_CANCER, C3_CANCER_WIDE

Control conditions not HLP_C3_DLBCL

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF8

NAME	C3_DLBCL_EXALLC
CONTROL_EXCLUDE	C3_CANCER\|C3_CANCER_WIDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS	!HLP_C3_DLBCL
SEX
INCLUDE	HLP_C3_DLBCL
PRE_CONDITIONS
CONDITIONS	HLP_C3_DLBCL
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	C833
COD_ICD_9	2000B
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO	ANY
CANC_TOPO_EXCL
CANC_MORPH	9680
CANC_MORPH_EXCL
CANC_BEHAV	3

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Or the full data table

Similar endpoints

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List of similar endpoints to Diffuse large B-cell lymphoma (controls excluding all cancers) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1010	434	576
Unadjusted prevalence (%)	0.27	0.21	0.35
Mean age at first event (years)	65.68	63.81	67.09

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.15	10.16 [6.62, 15.58]	2.4e-26	267
15 years	0.01	1.80 [1.11, 2.92]	1.7e-2	41
5 years	0.01	6.57 [3.79, 11.39]	2.1e-11	80
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_DLBCL_EXALLC – Diffuse large B-cell lymphoma (controls excluding all cancers)
GWS hits:

Survival analyses between endpoints

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Plot

before Diffuse large B-cell lymphoma (controls excluding all cancers)
after Diffuse large B-cell lymphoma (controls excluding all cancers)

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Table

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Drugs most likely to be purchased after Diffuse large B-cell lymphoma (controls excluding all cancers)

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Endpoint not on priority list, no data to show.