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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_COLON_ADENO_EXALLC for full statistics.

Colon adenocarcinoma

C3_COLON_ADENO

colon adenocarcinoma: An adenocarcinoma arising from the colon. It is more frequently seen in populations with a Western type diet and in patients with a history of chronic inflammatory bowel disease. Signs and symptoms include intestinal bleeding, anemia, and change in bowel habits. According to the degree of cellular differentiation, colonic adenocarcinomas are divided into well, moderately, and poorly differentiated. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

HLP_C3_COLON_ADENO

3180

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Check pre-conditions, main-only, mode, registry filters

Cause of death: ICD-10 C18
Cause of death: ICD-9 153
Cause of death: ICD-8 153
Cancer registry: Topography ICD-O-3 C18
Cancer registry: Morphology ICD-O-3 8140
Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

3180

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Check minimum number of events None

3180

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Include endpoints

3180

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Remove individuals based on genotype QC

3084

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C3_COLON_ADENO

Control definitions

Control conditions not HLP_C3_COLON_ADENO

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF8

Summary Statistics

Key figures

All Female Male
Number of individuals 3084 1286 1798
Unadjusted prevalence (%) 0.82 0.61 1.08
Mean age at first event (years) 68.25 66.60 69.43

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: C3_COLON_ADENO – Colon adenocarcinoma
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Colon adenocarcinoma

Endpoint not on priority list, no data to show.