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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_CML_EXALLC for full statistics.

Chronic myeloid leukaemia

C3_CML

obsolete_chronic myeloid leukemia: ['Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.']

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Cause of death: ICD-10 C92.1
Cause of death: ICD-9 2051A
Cause of death: ICD-8 20515
Cancer registry: Topography ICD-O-3 ANY
Cancer registry: Morphology ICD-O-3 9863|9875
Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

114

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Check minimum number of events None

114

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Include endpoints None

114

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Remove individuals based on genotype QC

106

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C3_CML

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF8

Summary Statistics

Key figures

All Female Male
Number of individuals 106 51 55
Unadjusted prevalence (%) 0.03 0.02 0.03
Mean age at first event (years) 55.51 54.58 56.37

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: C3_CML – Chronic myeloid leukaemia
GWS hits:

Survival analyses between endpoints

Plot

before Chronic myeloid leukaemia
after Chronic myeloid leukaemia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Chronic myeloid leukaemia