This is a non-core endpoint: only basic statistics are computed.
See its core counterpart C3_AML_EXALLC for full statistics.
Acute myeloid leukaemia
C3_AML
acute myeloid leukemia: Acute myeloid leukemia (AML) is a group of neoplasms arising from precursor cells committed to the myeloid cell-line differentiation. All of them are characterized by clonal expansion of myeloid blasts. AML manifests by fever, pallor, anemia, hemorrhages and recurrent infections.
Endpoint definition
↥
FinnGen phenotype data
392423 individuals
Apply sex-specific rule None
392423
Check conditions
HLP_C3_AML
257
Check pre-conditions, main-only, mode, registry filters
Cause of death: ICD-10
C92.0
Cause of death: ICD-9
2050A
Cause of death: ICD-8
20500
Cancer registry: Topography ICD-O-3
ANY
Cancer registry: Morphology ICD-O-3
9840|9861|986[67]|987[1-4]|989[1567]|9910|9920|993[01]
Cancer registry: Behaviour codes
3
2 out of 7 registries used, show all original rules.
257
Check minimum number of events None
257
Remove individuals based on genotype QC
231
C3_AML
Control definitions
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF8
Show upset plot detailing case counts by codes
Or the full data table
Similar endpoints
↥List of similar endpoints to
Acute myeloid leukaemia
based on the number of shared cases.
Broader endpoints:
- Acute myeloid leukaemia (controls excluding all cancers)
- Acute myeloid leukaemia
- Any event in cancer register
- Neoplasms
- Co-morbidities of interest (NEURO)
Narrower endpoints:
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 231 | 88 | 143 |
| Unadjusted prevalence (%) | 0.06 | 0.04 | 0.09 |
| Mean age at first event (years) | 61.52 | 55.02 | 65.53 |
Mortality
Not a core endpoint, no data to show.
Age distribution of first events
Year distribution of first events
Cumulative Incidence
Not a core endpoint, no data to show.
Correlations
↥
Index endpoint: C3_AML – Acute myeloid leukaemia
GWS hits:
Survival analyses between endpoints
↥Plot
before Acute myeloid leukaemia
after Acute myeloid leukaemia
Loading survival analyses plot
Table
Loading survival analyses table