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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_AML_EXALLC for full statistics.

Acute myeloid leukaemia

C3_AML

acute myeloid leukemia: Acute myeloid leukemia (AML) is a group of neoplasms arising from precursor cells committed to the myeloid cell-line differentiation. All of them are characterized by clonal expansion of myeloid blasts. AML manifests by fever, pallor, anemia, hemorrhages and recurrent infections.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

HLP_C3_AML

257

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Check pre-conditions, main-only, mode, registry filters

Cause of death: ICD-10 C92.0
Cause of death: ICD-9 2050A
Cause of death: ICD-8 20500
Cancer registry: Topography ICD-O-3 ANY
Cancer registry: Morphology ICD-O-3 9840|9861|986[67]|987[1-4]|989[1567]|9910|9920|993[01]
Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

257

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Check minimum number of events None

257

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Include endpoints

257

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Remove individuals based on genotype QC

231

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C3_AML

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF8

Summary Statistics

Key figures

All Female Male
Number of individuals 231 88 143
Unadjusted prevalence (%) 0.06 0.04 0.09
Mean age at first event (years) 61.52 55.02 65.53

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: C3_AML – Acute myeloid leukaemia
GWS hits:

Survival analyses between endpoints

Plot

before Acute myeloid leukaemia
after Acute myeloid leukaemia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acute myeloid leukaemia