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This is a non-core endpoint: only basic statistics are computed.

Non-allergic asthma

ASTHMA_NONALLERG

asthma: A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors resulting in recurring periods of wheezing (a whistling sound while breathing), chest tightness, shortness of breath, mucus production and coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

not (J10_ASTHMA_OTHER_THAN_NONALLERGIC
or L12_ATOPIC
or ALLERG_RHINITIS
or H7_ALLERGICCONJUNCTIVITIS
or FOOD_ALLERGY
or Z21_DESEN_ALLERGE
or POLLENALLERG

326097

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

2824

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Remove individuals based on genotype QC

2703

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ASTHMA_NONALLERG

Control definitions

Control conditions not (L12_ATOPIC
or ALLERG_RHINITIS
or H7_ALLERGICCONJUNCTIVITIS
or FOOD_ALLERGY
or Z21_DESEN_ALLERGE
or POLLENALLERG

Extra metadata

First used in FinnGen datafreeze DF9

Summary Statistics

Key figures

All Female Male
Number of individuals 2703 1513 1190
Unadjusted prevalence (%) 0.72 0.72 0.72
Mean age at first event (years) 50.52 48.46 53.13

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: ASTHMA_NONALLERG – Non-allergic asthma
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Non-allergic asthma

Endpoint not on priority list, no data to show.