Use of disulfiram, acamprosate or naltrexone

ALCO_PRESCRIPTION

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Medicine purchases: ATC N07BB01|N07BB03|N07BB04

1 out of 7 registries used, show all original rules.

2767

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Check minimum number of events

Min. number of events 3

2767

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Include endpoints None

2767

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Remove individuals based on genotype QC

2699

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ALCO_PRESCRIPTION

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 2699 881 1818
Unadjusted prevalence (%) 0.72 0.42 1.09
Mean age at first event (years) 42.91 41.25 43.71

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.27 [1.83, 5.86] 6.7e-5 176
15 years 0.02 2.94 [1.83, 4.73] 8.9e-6 100
5 years 0.00 2.80 [1.64, 4.79] 1.6e-4 24
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: ALCO_PRESCRIPTION – Use of disulfiram, acamprosate or naltrexone
GWS hits: 1

Survival analyses between endpoints

Plot

before Use of disulfiram, acamprosate or naltrexone
after Use of disulfiram, acamprosate or naltrexone

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Use of disulfiram, acamprosate or naltrexone

Endpoint not on priority list, no data to show.