Use of disulfiram, acamprosate or naltrexone

ALCO_PRESCRIPTION

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Medicine purchases: ATC N07BB01|N07BB03|N07BB04

1 out of 7 registries used, show all original rules.

2767

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Check minimum number of events

Min. number of events 3

2767

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Include endpoints None

2767

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Remove individuals based on genotype QC

2699

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ALCO_PRESCRIPTION

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

NAME	ALCO_PRESCRIPTION
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC	N07BB01\|N07BB03\|N07BB04
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Use of disulfiram, acamprosate or naltrexone based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2699	881	1818
Unadjusted prevalence (%)	0.72	0.42	1.09
Mean age at first event (years)	42.91	41.25	43.71

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.27 [1.83, 5.86]	6.7e-5	176
15 years	0.02	2.94 [1.83, 4.73]	8.9e-6	100
5 years	0.00	2.80 [1.64, 4.79]	1.6e-4	24
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ALCO_PRESCRIPTION – Use of disulfiram, acamprosate or naltrexone
GWS hits: 1

Survival analyses between endpoints

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Plot

before Use of disulfiram, acamprosate or naltrexone
after Use of disulfiram, acamprosate or naltrexone

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Use of disulfiram, acamprosate or naltrexone

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Endpoint not on priority list, no data to show.