This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Alzheimer’s disease (Early onset)
AD_EO
Alzheimer's disease: A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language.
Endpoint definition
↥
FinnGen phenotype data
392423 individuals
Apply sex-specific rule None
392423
Check conditions None
392423
Check pre-conditions, main-only, mode, registry filters
Hospital Discharge: ICD-10
F00.0*, F00.00*, F00.00*G30.0, G30.0, G30.0+F00.00
Cause of death: ICD-10
F00.0*, F00.00*, F00.00*G30.0, G30.0, G30.0+F00.00
2 out of 7 registries used, show all original rules.
1366
Check minimum number of events None
1366
Include endpoints None
1366
Remove individuals based on genotype QC
1314
AD_EO
Control definitions
Control exclude
G6_ALZHEIMER
Extra metadata
First used in FinnGen datafreeze
DF2
Show upset plot detailing case counts by codes
Or the full data table
Similar endpoints
↥List of similar endpoints to
Alzheimer’s disease (Early onset)
based on the number of shared cases.
Broader endpoints:
- Alzheimer’s disease (Early onset) (more control exclusions)
- Alzheimer’s disease, wide definition
- Alzheimer’s disease, wide definition (more control exclusions)
- Any dementia
- Any dementia (more control exclusions)
Narrower endpoints:
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1314 | 599 | 715 |
| Unadjusted prevalence (%) | 0.35 | 0.28 | 0.43 |
| Mean age at first event (years) | 74.81 | 73.41 | 75.99 |
Mortality
Not a core endpoint, no data to show.
Age distribution of first events
Year distribution of first events
Cumulative Incidence
Not a core endpoint, no data to show.
Correlations
↥
Index endpoint: AD_EO – Alzheimer’s disease (Early onset)
GWS hits:
Survival analyses between endpoints
↥Not a core endpoint, no data to show.
Drugs most likely to be purchased after Alzheimer’s disease (Early onset)
↥Endpoint not on priority list, no data to show.