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Viral infections characterized by skin and mucous membrane lesions

DOID EFO MESH SNOMED PheWeb

AB1_VIRAL_SKIN_MUCOUS_MEMBRANE

rubella: A viral infectious disease that results_in infection located_in skin, has_material_basis_in Rubella virus, which is transmitted_by droplet spread of oronasal secretions from the infected person through coughing and sneezing, and transmitted_by congenital method. The infection has_symptom rash on the face which spreads to the trunk and limbs, has_symptom fever, has_symptom lymphadenopathy, has_symptom joint pains, has_symptom headache, and has_symptom conjunctivitis. [ url:http://en.wikipedia.org/wiki/Rubella ]

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 B00-B09
Hospital discharge: ICD-9 078[0-4]
Hospital discharge: ICD-8 079[0-1]
Hospital discharge: excluded ICD-9 0781C|0785|078[7-8]
Cause of death: ICD-10 B00-B09
Cause of death: ICD-9 078[0-4]
Cause of death: ICD-8 079[0-1]
Cause of death: excluded ICD-9 0781C|0785|078[7-8]

2 out of 7 registries used, show all original rules.

11625

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Check minimum number of events None

11625

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Include endpoints

14772

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Remove individuals based on genotype QC

14280

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AB1_VIRAL_SKIN_MUCOUS_MEMBRANE

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Viral infections characterized by skin and mucous membrane lesions based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 14280 7821 6459
Unadjusted prevalence (%) 3.79 3.71 3.88
Mean age at first event (years) 43.85 44.71 42.81

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.01 [2.42, 3.76] 1.2e-22 1210
15 years 0.01 1.54 [1.26, 1.87] 1.8e-5 457
5 years 0.00 3.22 [2.72, 3.82] 1.7e-41 377
1 year 0.00 8.86 [7.30, 10.75] <1e-100 218

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: AB1_VIRAL_SKIN_MUCOUS_MEMBRANE – Viral infections characterized by skin and mucous membrane lesions
GWS hits: 2

Survival analyses between endpoints

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Plot

before Viral infections characterized by skin and mucous membrane lesions
after Viral infections characterized by skin and mucous membrane lesions

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Drugs most likely to be purchased after Viral infections characterized by skin and mucous membrane lesions

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Endpoint not on priority list, no data to show.