Protozoal diseases

AB1_PROTOZOAL

toxoplasmosis: A parasitic disease contracted by the ingestion or fetal transmission of toxoplasma gondii.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 B50-B64
Hospital discharge: ICD-9 08[4-6]|130|136[3-4]|0889
Hospital discharge: ICD-8 08[6-7]|130|084|13601
Cause of death: ICD-10 B50-B64
Cause of death: ICD-9 08[4-6]|130|136[3-4]|0889
Cause of death: ICD-8 08[6-7]|130|084|13601

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Remove individuals based on genotype QC

663

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AB1_PROTOZOAL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 663 341 322
Unadjusted prevalence (%) 0.18 0.16 0.19
Mean age at first event (years) 51.67 48.74 54.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.49 [1.25, 9.79] 1.7e-2 107
15 years 0.00 0.78 [0.33, 1.84] 5.6e-1 16
5 years 0.01 4.71 [2.41, 9.20] 5.8e-6 27
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: AB1_PROTOZOAL – Protozoal diseases
GWS hits:

Survival analyses between endpoints

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Plot

before Protozoal diseases
after Protozoal diseases

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Drugs most likely to be purchased after Protozoal diseases

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Endpoint not on priority list, no data to show.