Protozoal diseases

AB1_PROTOZOAL

toxoplasmosis: A parasitic disease contracted by the ingestion or fetal transmission of toxoplasma gondii.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 B50-B64
Hospital discharge: ICD-9 08[4-6]|130|136[3-4]|0889
Hospital discharge: ICD-8 08[6-7]|130|084|13601
Cause of death: ICD-10 B50-B64
Cause of death: ICD-9 08[4-6]|130|136[3-4]|0889
Cause of death: ICD-8 08[6-7]|130|084|13601

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Remove individuals based on genotype QC

663

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AB1_PROTOZOAL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 663 341 322
Unadjusted prevalence (%) 0.18 0.16 0.19
Mean age at first event (years) 51.67 48.74 54.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.49 [1.25, 9.79] 1.7e-2 107
15 years 0.00 0.78 [0.33, 1.84] 5.6e-1 16
5 years 0.01 4.71 [2.41, 9.20] 5.8e-6 27
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: AB1_PROTOZOAL – Protozoal diseases
GWS hits:

Survival analyses between endpoints

Plot

before Protozoal diseases
after Protozoal diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Protozoal diseases

Endpoint not on priority list, no data to show.